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Penicillin
Cocktail recipe

Rating

4.34 / 5

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The Penicillin cocktail is a modern classic renowned for its harmonious blend of smoky and sweet flavors with a zesty... ... more

The Penicillin cocktail is a modern classic renowned for its harmonious blend of smoky and sweet flavors with a zesty citrus kick. The cocktail is typically based on a mixture of whiskey—often incorporating both blended Scotch and a peated single malt for depth—as well as the spicy warmth of ginger liqueur.

The addition of lemon juice brings a refreshing acidity to the drink, while honey syrup rounds it out with a smooth sweetness. Served in a lowball glass, the Penicillin offers a complex and soothing flavor profile that has made it a favorite among cocktail aficionados seeking a bold yet balanced libation.

Check out all our FAQ's on this cocktail

Microbadges

Cocktail Of The Day
Base ingredient
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Whiskey
Calories
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153 calories
Garnish
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Pineapple
Alcohol content
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24.47% | 2.52 units *

Lowball / rocks glass

Ingredients

oz
ml
cl
Serves:
-
+
cocktail colin avatar

Cocktail Colin says:

4/5

The Penicillin cocktail masterfully combines the smokiness of whiskey with the sharp zest of lemon juice and the sweet warmth of honey and ginger liqueur, creating a truly therapeutic mixture. Its intricate balance of bold, smoky elements with refreshing citrus and spicy hints makes it appealing for those who appreciate a cocktail with depth and complexity.

Method
How to make a Penicillin

Serves 1 · Takes 3 minutes
Whiskey 30ml, Whiskey 30ml, Ginger liqueur 7.5ml, Lemon Juice 20ml, Honey syrup 15ml
Add all the ingredients into a cocktail shaker with ice
Strain into a ice-filled rocks glass
Garnish with a pineapple chunk and serve

Power tips
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Incorporate a peat-forward single malt whiskey as a float over the finished drink instead of mixing it in, ensuring a distinct smoky aroma with each sip.
Use fresh ginger juice if available, instead of ginger liqueur, for a more intense and natural ginger heat.
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Learn more about some of the mixology terms used in this cocktail

·  Strain  ·  Garnish  · 

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Comments

FAQ's

Faq icon

Who invented the Penicillin cocktail and when?

The Penicillin cocktail was invented by Sam Ross in 2005 at the Milk & Honey bar in New York City. It quickly became a modern classic, known for its distinctive combination of smoky, spicy, and sweet flavors.

Ingredient specifics icon

What is the significance of using two types of whiskey in the Penicillin cocktail?

Using two types of whiskey in the Penicillin cocktail creates a complex flavor profile. Typically, a blend of smoky Scotch and a smoother whiskey like a single malt or blended Scotch is used. The smoky Scotch adds a deep, peaty flavor, while the smoother whiskey balances it with a milder, sweeter taste, enhancing the cocktail's overall depth and character.

Ingredient substitutions icon

Can I substitute honey syrup with regular honey in the Penicillin cocktail?

Yes, you can substitute honey syrup with regular honey in the Penicillin cocktail, but you might need to adjust the consistency. Honey syrup is typically made by diluting honey with water, making it easier to mix into the cocktail. If using regular honey, consider warming it slightly or mixing it with a bit of hot water to achieve a consistency that will blend smoothly into the drink.

Garnishing tips icon

What is the best way to garnish the Penicillin cocktail?

The Penicillin cocktail is often garnished with a piece of candied ginger or a lemon twist. The candied ginger complements the ginger liqueur used in the drink, and the lemon twist adds a fragrant, citrus aroma that enhances the cocktail's flavors without overpowering them.

Faq icon

How do I make honey syrup for the Penicillin cocktail?

To make honey syrup for the Penicillin cocktail, combine equal parts honey and hot water in a container. Stir until the honey dissolves completely. Allow the syrup to cool before using it in your cocktail. This syrup can be stored in a sealed container in the refrigerator for up to two weeks. Adjust the honey-to-water ratio based on your sweetness preference.

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